Microfluidic Multi Cell Cultivation with automatic Sample Handling
The BioSynthesizer technology now fits to a robot called 2-level-Lab BSys 4.2 with elevated work deck. It is made to operate small transparent bio containments, e.g. SBS well format objects, microfluidic cartridges and others. It features two tool heads for optical inspection in both directions. The upper tool head operates all GeSiM made tools for liquid handling, Nanolitre pipetting and paste dispensing. The modular approach of all GeSiM instruments enables even 3D printing. Microfluidic cartridges and chips can be provided by GeSiM but this instrument also accepts customer designs.
The 2-level-lab robot is always configured to a particular application. It was designed for unattended run of complex sequences in cell labs, e.g. printing and cultivation of 3D organoids with one setup.
This example accommodates an array of Multi-Organ-Chips (MOCs) on the left tray. Each MOC hooks up to a separate control unit for media and temperature adjustment. The MOC design can be adapted to different applications.
Sytemic toxicity testing
- Two parallel-connected cell culture chambers (3), reservoir (2)
- 3-point-peristaltic-pump (1), inlet and outlet valves (4)
- Temperature controlled support
- Oxygen control directly on culture media
- External gas mixer
- Gas permeable membrane for in/output
Please contact us with your specific idea.