Category Archives: Basic-Features


Customizable Platform for Bioprinting

At a Glance

The BioScaffolder(BS) 3.1 is different from most common 3D printers: Biopolymers for tissue engineering are still under development. Printing from cartrigde enables the use of home made polymer blends. BS31 is not limited to commercially available filaments as known from the many FDM printers. Further very different printing methods for different materials can be combined at one instrument.

This section introduces to the pneumatic extruders as core component of each shipped BS31. The next tab (Second) elaborates available options for individual configurations.

A more common introduction to the world of bioscaffolds and tissue engineering is given at the BIOSCAFFOLD tab. Selected customer applications are described at the APPLICATIONS tab.


  • Three pneumatic extruders (Optionally heated) for dispensing of high-viscous/ pasty materials. Individual print parameters for each axes
  • Automatic alignment for tools and building platform
  • Nozzle cleaner


YouTube: Introduction to BS3.1 (HD)


OPTIONS (Next Tab): GeSiM enhances the range of add-on modules for combination with the basic pneumatic extruders. At a glance:


  • Heatable (120°C), coolable (From Autumn 2017) cartridge holders
  • Pipetting unit (Low-viscous liquid handling with pipet tips or piezoelectric Nanoliter dispenser)
  • Twin-Tip pipetting unit for mixing up tiny droplets (Low-viscous liquids)
  • Piezoelectric dispense valves for high-viscous materials (Third party)
  • Pneumatic Core/Shell extruders for doing hollow fibres
  • Melt Electrospinning, -writing (MES)
  • High-Power Syringe Extruders for melts up to 250°C
  • Exposition Lamps for Curing and UV-Hardening
  • FDM extruder printing commercial filaments
  • Trays for target objects, e.g. cell culture plates
  • Software for Import of STL data


User interface of the Scaffold-Gernerator of BS3.1

User interface of the Scaffold-Generator of BS3.1

The Scaffold Generator of the BS3.1 software creates print maps for the BS3.1 without external CAD programs. Basic geometric figures can be selected and parametrized. Bioscaffolds usually require certain interior layouts with defined porosity. These parameters are difficult to edit with public CAD programs or STL processors.
The interface between the Scaffold Generator and the instrument is based on Gcode.


BS3.1 adapts to your application as well as to your budget!


Pneumatic Extrusion

Computers, Cartridges and Pressurized Air: The heart of each BS3.1

30ml, 10ml cartridges (Nordson GLT)

30ml, 10ml cartridges (Nordson GLT)

F-Box BS3.1

F-Box BS3.1

BS3.1 comprises an external “F-Box” (Right picture) managing the media supply and removal for the instrument. Furthermore it contains the control computer of the instrument.


The basic pneumatic extruder allows individual pressure settings. BS3.1 supports 10 ml and 30ml cartridges (Left picture). Pressure ranges from 0 to 7 bar.

Tools & Calibration

Many Tools, Different Materials: Click and Go!

Z-Sensor for ground calibration

Z-height-sensor for ground calibration


Biomaterials of very different consistencies require very different tools (sizes) but need to be printed into one structure.




On top of this, any 3D printer works only when the first layer is well aligned to the building platform. The BS3.1 comes with optical and mechanical calibration tools for the automatic offset compensation between the tools and the ground level. The only things you have to do is load your material, find the right pressure for extrusion and create your model. Then you are just a few mouse clicks away from your ready printed scaffold.



BS3.1 combines different tools for building 3D structures with several materials

BS3.1 combines different tools for building 3D structures with several materials


We speak G-code!

How to talk to BS3.1

The BioScaffolder 3.1 receives G-code data from the control software. It is a commonly used programming language for NC (numeric control) machines. G-code is always hardware dependent, therefore a lof of different G-code flavors exist.

A reference of the GeSiM BS31 gcode commands is available for download here.

Disclaimer: GeSiM isn’t responsible for damages of the hardware due to wrong and/or unappropriated G-code sequences sent to the machine. If you are not sure contact GeSiM in advance.