Category Archives: Basic-Features


Customizable Platform for Bioprinting

At a Glance

The BioScaffolder (BS) printer family comprises BS3.2 with focus on research and BS4.2 offering production capabilities. Main applications are:

- 3D Printing of very different (Bio-)polymers
- Creation of porous structures for tissue engineering
- Co-printing of hard (E.g. PCL/PLA) and soft (E.g. Alginate) biopolymers (Sequential printing, co-axial extrusion, Nanolitre pipetting)
- Functionalization of metal implants with soft polymer layers
- Printing of micro structures from biopolymers by melt electro spinning/writing
BioScaffolder instrument lines: Benchtop version BS3,2 (left side), larger BS4.2 (right side) with safety cabinet

BioScaffolder instrument lines: Benchtop version BS3.2 (left side), larger BS4.2 (right side) with safety cabinet

Printing from cartrigde enables the use of home made polymer blends. BS printers are not limited to commercially available filaments as known from the many FDM printers. Further very different printing methods for different materials can be combined on a single instrument.

Each BS printer comes with three pneumatic extruders but adapts to a wide range of materials by numerous add-on modules. Both printing tools and software are almost identical for most BS printers.

A more common introduction to the world of bioscaffolds and tissue engineering is given at the BIOSCAFFOLD tab. Selected customer applications are described at the APPLICATIONS tab.

BS4.2 offers approx. double space for print targets than BS3.2.



  • Three pneumatic extruders (Optionally heated) for dispensing of high-viscous/ pasty materials. Individual print parameters for each axes
  • Automatic alignment for tools and building platform
  • Nozzle cleaner


YouTube: Introduction to BS3.1 (HD)


OPTIONS (Next Tab): GeSiM enhances the range of add-on modules for combination with the basic pneumatic extruders. At a glance:


  • Heatable (190°C), coolable cartridge holders
  • Pipetting unit (Low-viscous liquid handling with pipet tips, solenoid dispense valve or piezoelectric Nanoliter dispenser)
  • Twin-Tip pipetting unit for mixing up tiny droplets (Low-viscous liquids)
  • Piezoelectric dispense valves for high-viscous materials (Third party)
  • Pneumatic Core/Shell extruders for doing hollow fibres
  • Melt Electrospinning, -writing (MES)
  • High-Power Syringe Extruders for melts up to 250°C
  • Exposition Lamps for Curing and UV-Hardening
  • FDM extruder printing commercial filaments
  • Trays for target objects, e.g. cell culture plates
  • Heatable (150°C), coolable (4°C, with external chiller bath) object trays
  • Software for Import of STL data


BS printers adapt to your application as well as to your budget! Don’t miss the documents on the right side of this article.


Pneumatic Extrusion

Computers, Cartridges and Pressurized Air: The heart of each BS printer

30ml, 10ml cartridges (Nordson GLT)

30ml, 10ml cartridges (Nordson GLT)

F-Box BS3.1

F-Box BS3.1

The BS comprises an external “F-Box” (Right picture) managing the media supply and removal for the instrument. Furthermore it contains the control computer of the instrument.


The basic pneumatic extruder allows individual pressure settings. BS printers support 10 ml and 30ml cartridges (Left picture). Pressure ranges from 0 to 6 bar.

Tools & Calibration

Many Tools, Different Materials: Click and Go!

Z-Sensor for ground calibration

Z-height-sensor for ground calibration


Biomaterials of very different consistencies require very different tools (sizes) but need to be printed into one structure.




On top of this, any 3D printer works only when the first layer is well aligned to the building platform. The BS printer come with optical and mechanical calibration tools for the automatic offset compensation between the tools and the ground level. The only things you have to do is load your material, find the right pressure for extrusion and create your model. Then you are just a few mouse clicks away from your ready printed scaffold.



BS3.1 combines different tools for building 3D structures with several materials

BS3.2 combines different tools for building 3D structures with several materials


We speak G-code!

How to talk to your BS printer

The BioScaffolder printer receives G-code data from the control software. It is a commonly used programming language for NC (numeric control) machines. G-code is always hardware dependent, therefore a lof of different G-code flavors exist.

A reference of the GeSiM BS gcode commands is available on request.

Disclaimer: GeSiM isn’t responsible for damages of the hardware due to wrong and/or unappropriated G-code sequences sent to the machine. If you are not sure contact GeSiM in advance.