Artificial Tissue from Maccaroni Strands
Soft matrices like Hydrogels are cell friendly materials but hard to print into stable 3D structures. The combination with more stiff thermoplastic scaffolds may cause biocompatibility issues.The pneumatic C/S-extruder (Core/Shell extruder) for BS printers allow to combine two materials with different properties in a coaxial manner. The tool is equipped with a kind of double nozzle with different but corresponding inner and outer diameter, respectively. The print parameters can be set individually for both channels in order to match properties of the respective bioinks.
A. R. Akkineni, T. Ahlfeld, A. Lode and M. Gelinsky: A versatile method for combining different biopolymers in a core/shell fashion by 3D plotting to achieve mechanically robust constructs, IOP Publishing Ltd., Oct 2016
Centre for Translational Bone, Joint and Soft Tissue Research
Technische Universität Dresden