Generated by Rank Math SEO, this is an llms.txt file designed to help LLMs better understand and index this website.

# GeSiM Bioinstruments and Microfluidics: Integrating the Worlds of Micro and Macro Technology

## Sitemaps
[XML Sitemap](https://gesim-bioinstruments-microfluidics.com/sitemap_index.xml): Includes all crawlable and indexable pages.

## Posts
- [From Lab to Real World Security: Chemical Detection Research](https://gesim-bioinstruments-microfluidics.com/security-chemical-detection/): At Cranfield University, Dr. Licia Dossi, Senior Lecturer and Chartered Scientist of the Royal Society of Chemistry, leads pioneering research in chemical detection, synthetic polymer chemistry, and energetic materials. Her work spans academic teaching, project management, and collaboration with public and private sectors, including leading the UK Centre of Excellence in Energetic Materials (CoEEM) - Explosives Detection Hub. The team’s projects combine scientific innovation with practical applications in security and environmental monitoring.
- [Fine Tuning Calcium Phosphate for Bioprinting](https://gesim-bioinstruments-microfluidics.com/calcium-phosphate-bioprints/): Calcium phosphate has long been one of the most trusted materials in orthopedics and regenerative medicine. Its chemical similarity to human bone, its biocompatibility, and its ability to support natural remodeling make it a reliable material in coatings, bone substitutes, and implantable devices. As the field moves toward more personalized and biologically relevant solutions, calcium phosphate is also emerging as a functional material for bioprinting.
- [Advancing Microbiological Water Monitoring with ECOPLAS: Fast, On Site E. coli Detection](https://gesim-bioinstruments-microfluidics.com/water-monitoring/): Real‑time microbiological water monitoring is no longer a distant goal. Culture‑based E. coli testing typically takes 24–72 hours, preventing timely operational decisions, which is why the ECOPLAS project is developing a compact, on-site measurement system for near-real-time detection of E. coli in freshwater, intended for applications such as water reuse, agricultural irrigation, bathing water surveillance, and raw water monitoring. The device is conceived for automated operation (sampling, measurement, regeneration, cleaning) and can be used as a portable unit, benchtop device, or fixed station, including remote deployment.
- [Collagen microcontact prints enable multiplexed assays in organotypic brain slices](https://gesim-bioinstruments-microfluidics.com/assays-in-brain-slices/): Professor Christian Humpel and his team at the Medical University of Innsbruck, Austria have developed a practical, imaging‑friendly platform that brings precise spatial control to living brain slices. Working with 150‑micrometer organotypic mouse slices cultured at the membrane interface, they preserve native three‑dimensional circuitry while applying localized biochemical cues. This approach lets the group study neuronal outgrowth, microglial activation, and vascular behavior in a single manipulable ex vivo system, and it reduces animal use by enabling multiple experimental conditions from the same brain.
- [Miniaturized Telomerase Assays Reveal Novel Inhibitor Interactions](https://gesim-bioinstruments-microfluidics.com/telomerase-assays/): Telomerase reverse transcriptase (TERT) plays a central role in cellular development, regeneration, and cancer biology. Because abnormal telomerase activity is linked to tumor progression and age‑related diseases, researchers have long sought reliable ways to identify compounds that can modulate its function. Traditional assays, however, are limited in throughput and reproducibility. This study set out to develop a highly miniaturized, microarray‑based platform to screen for telomerase‑binding compounds more efficiently and with greater sensitivity.
- [Bioinstruments Customer Symposium at GeSiM, Radeberg](https://gesim-bioinstruments-microfluidics.com/bioinstruments-symposium/): We are pleased to invite you to GeSiM’s 30-year anniversary celebration. It is the perfect occasion for a bioinstruments customer symposium, to be held close to our premises in Radeberg, Germany. Talk to customers and learn about their scientific work supported by GeSiM instruments.
- [Self-Healing Ionogels Modeled After Spider Silk](https://gesim-bioinstruments-microfluidics.com/self-healing-ionogels/): Ionogels are three-dimensional polymer matrices infused with ionic liquids (ILs), offering unique properties such as high ionic conductivity, thermal and chemical stability, environmental resilience, and flexibility. Despite their advantages, ionogel-based devices are prone to damage and functional degradation over time, leading to reduced performance or failure.
- [GeSiM Partners with Yuri on Pioneering a 3D bioprinter for space](https://gesim-bioinstruments-microfluidics.com/3d-bioprinter-for-space/): Yuri, a leading space biotechnology company, has initiated a groundbreaking project: the development of the first European 3D bioprinter for space. Specializing in the use of the microgravity environment of space to develop and manufacture superior biotech products, Yuri has consistently pushed the boundaries of what is possible in biotechnology. They develop modular bioreactors and incubators for cell cultures, protein crystals, and plants, which they launch to the International Space Station (ISS) and other spacecraft such as the Sierra Nevada Dream Chaser and SpaceX Dragon. They also sell and rent devices to simulate microgravity on Earth, expanding the scope of their innovative solutions.
- [Precision DNA-Based Analysis for Pathogen Identification in Laboratory Medicine](https://gesim-bioinstruments-microfluidics.com/pathogen-identification-for-laboratory-medicine/): The team of Cube Dx gathered experience with various technologies and instruments for DNA microarray production for laboratory medicine. Cylindrical microarrays – hybcells – are the core product of the IVD company. Cube Dx’ hybcells are a tool for sensitive and specific DNA-based identification of more than 130 microorganisms causing bacterial and fungal infections. The technology offers a drastic reduction of time to diagnosis and treatment of critically ill patients.
- [Integrating FDM and Inkjet Printing for Personalized Drug-Loaded Tablets](https://gesim-bioinstruments-microfluidics.com/drug-loaded-tablets/): In this context, researchers from the Universidade Federal de Juiz de Fora and the University of Greenwich conducted a study to combine Fused Deposition Modeling (FDM) and inkjet printing for the development of 3D-printed drug-loaded tablets. This innovative approach aims to elevate precision, reproducibility, and adaptability in personalized medicine. FDM was utilized to fabricate plain polyvinyl alcohol (PVA) tablets, followed by inkjet printing to dispense minoxidil ethanolic solutions with high accuracy. Two solvent systems, 70% ethanol v/v (P70) and absolute ethanol (P100), were explored to understand their impact on solvent miscibility, drug absorption, and crystal formation on the tablet surfaces.
- [Long-Lasting Ocular Implants for Posterior Eye Diseases](https://gesim-bioinstruments-microfluidics.com/ocular-implants-for-eyes/): Current treatments, such as intravitreal injections of anti-VEGF agents, are costly and may hinder equitable healthcare access. Consequently, there is a pressing need for alternative therapies. Researchers from Queen’s University Belfast, Airlangga University and University of Seville have addressed this need by developing axitinib-loaded polymeric ocular implants to treat posterior ocular diseases, including DR and AMD.
- [Refining RPPA Techniques for Accurate Quantification of Phosphoproteins in Solid Tissues](https://gesim-bioinstruments-microfluidics.com/rppa-for-phosphoproteins/): The Reverse Phase Protein Array (RPPA) is a robust technique for quantitative proteomics, particularly useful for profiling post-translational modifications (PTMs) in finite tissue samples such as those from patients. Despite efforts to optimize tissue-based RPPA applications, technical challenges remain, including the validation of RPPA-applicable antibodies, which is crucial for accurate quantification.
- [3D Bioprinted Breast Cancer Models for Enhanced Drug Testing and Metabolic Studies](https://gesim-bioinstruments-microfluidics.com/breast-cancer-models/): Despite advancements in modeling the complex tumor microenvironment, conventional breast cancer models often fall short in providing accurate insights into cancer biology and drug efficacy. Accurately modeling this environment could improve the efficacy and safety of cancer treatments by offering more accurate preclinical models that mimic in vivo conditions, addressing issues like therapy resistance and metabolic diversity in tumors.
- [Efficient Microalgae Separation Using Dielectrophoresis in a Microfluidic Flow Cell](https://gesim-bioinstruments-microfluidics.com/microalgae-separation/): Microalgae are a valuable source of poly-unsaturated fatty acids, which are applied in various biotechnological fields such as pharmaceuticals and food supplements. Separating microalgae cells based on their lipid content could be relevant for at-line analytical techniques and strain selection.
- [Advancing Cancer Research with 3D Bioprinting Realistic Models](https://gesim-bioinstruments-microfluidics.com/bioprinting-cancer-research/): A team of researchers at McGill University has made significant strides in this area by utilizing 3D extrusion bioprinting with a composite bioink containing reinforced decellularized extracellular matrix (ECM) hydrogel to fabricate an in-vitro model of head and neck cancer. This model incorporates fibroblasts, representing the stromal component, and HNSCC cells, representing the tumor cells.
- [Bioink for 3D-Bioprinting with Decellularized Bone Particles](https://gesim-bioinstruments-microfluidics.com/bioinks-for-3d-bioprinting/): The incorporation of decellularized bone (DB) particles into the bioink formulation can significantly enhance the outcome of biofabrication. DB particles, derived from natural bone extracellular matrix (ECM) proteins and the biomineralization property of bone tissue, can enhance the proliferation and osteogenic differentiation of cells within the bioink formulations when used as an additive in the GEL matrix. This is because the natural bone ECM proteins and the biomineralization property of bone tissue can provide a more natural environment for the cells, thereby enhancing their behavior.
- [Controlled Release of Growth Factors in Bioprinted Respiratory Scaffolds](https://gesim-bioinstruments-microfluidics.com/growth-factors-in-scaffolds/): Tissue engineering is a rapidly evolving field that seeks to stimulate and control tissue generation and regeneration by incorporating cells, biocompatible materials, and bioactive molecules. Both the mechanical and chemical environments provide cues and signaling factors that significantly influence cellular development. Among these, growth factors are key signaling molecules in the biochemical environment that play a crucial role in initiating and regulating cellular activities.
- [Tissue Engineering with combination of FDM and MEW](https://gesim-bioinstruments-microfluidics.com/combination-of-fdm-and-mew/): Researchers at the University of Otago aimed to combine two additive manufacturing techniques—fused deposition modeling (FDM) and melt electrowriting (MEW)—to create branched, hollow scaffolds for vascularization.
- [Transforming Tendon Reconstruction: The GeSiM BioScaffolder’s Role in Hybrid Scaffold Innovation](https://gesim-bioinstruments-microfluidics.com/tendon-reconstruction/): In a recent study published in the journal Biomaterials Advanced, authors proposed a new approach to fabricate 3D scaffolds for tendon reconstruction using a combination of two biofabrication techniques: embroidery and melt electrowriting (MEW).
- [Revolutionizing Food Safety: Lab-in-a-Package](https://gesim-bioinstruments-microfluidics.com/lab-in-a-package/): In a world where food safety is essential, a paper published by researchers at the McMaster University (CA), GeSiM’s customer, introduces a game-changing solution: Lab-in-a-Package. This innovative approach aims to transform the way we detect and prevent foodborne illnesses, offering a hands-free, real-time method within the confines of a closed food package.
- [LifeCare’s Cutting-Edge Approach: GeSiM Machines Enable Series Production of Chip-based Glucose Sensor](https://gesim-bioinstruments-microfluidics.com/lifecare-glucose-sensor/): LifeCare, a forward-thinking medical sensor company, recently published a groundbreaking move towards automated production through a strategic purchase order from GeSiM mbH. This significant step not only demonstrates LifeCare's commitment to advancing medical sensor technology but also showcases the incredible flexibility and customization capabilities of GeSiM machines in handling complex and non-standard applications.
- [A GeSiM Bioprinter beyond Gravity](https://gesim-bioinstruments-microfluidics.com/bioprinter-beyond-gravity/): A team from Dresden University Hospital has now tested a GeSiM bioprinter in a non-gravitational environment. The device was taken on board of an AIR ZERO G aircraft and put into operation there. During several parabolic flights, it was possible to demonstrate that the device functions perfectly in a micro-G environment.
- [Multi-Material Printing: An Approach to Chemofluidic Valves for Microfluidic Applications](https://gesim-bioinstruments-microfluidics.com/chemofluidic-valves/): The presented microfluidic chip is based on a multilayer system with laminated separating layers and fluid-conducting layers. Laser-engraved PMMA or PE films were used for the individual layers. Figure 1 shows the basic structure. Using the BioScaffold Printer BS3.2 from GeSiM, very different materials were applied at the positions of the chemofluidic valves: An UV-curable Hydrogel was dispensed by piezoelectric nozzles to make normally open valves. These valves are closing by contact with water. PEG (molar weight approx. 35.000 g/mol) was extruded pneumatically at a temperature of 92°C (198 °F) for the normally closed valves.
- [Bioinstruments and Microfluidics at the BioCHIP Berlin Conference, 13. /14.06.2023](https://gesim-bioinstruments-microfluidics.com/bioinstruments-and-microfluidics-at-the-biochip-berlin-conference-13-14-06-2023/): There are many options to make elements like wells and channels on microfluidic components and biochips, including biochemical activation: Lithography based etching techniques, 3D printing, direct writing with piezoelectric Nanolitre dispensers, Nanoimprint lithography (NIL), microcontact printing and more. GeSiM offers tools and know-how for almost all these technologies.
- [GeSiM bioinstruments at SLAS2023, San Diego (USA), 25th Feb to 1st March](https://gesim-bioinstruments-microfluidics.com/gesim-at-slas2023/): SLAS2023 International Conference and Exhibition is around the corner. It will attract scientists from all over the world, comprising a large commercial exhibition and a scientific conference. SLAS2023 will be focused on laboratory automation and more.
- [MEW of Liquid Crystal Elastomer Scaffolds with Programmed Mechanical Response](https://gesim-bioinstruments-microfluidics.com/mew-of-lce-scaffolds/): MEW - Melt Electro Writing - means the deposition of thin fibres by electrostatic forces, following exactly pre-programmed patterns. With GeSiM BioScaffold printers, the MEW printhead deposits Gcode based geometries in the same way a pneumatic extruder does.
- [Liquid Handling & Bioprinting at MEDICA 2022](https://gesim-bioinstruments-microfluidics.com/liquid-handling-bioprinting-at-medica-2022/): MEDICA will open its doors again from November 14th to 17th. For the first time since 2019, GeSiM will also present new products (GeSiM: Hall 1, E24).
- [Real-Time Monitoring of individual Spots on the Nano-Plotter](https://gesim-bioinstruments-microfluidics.com/real-time-monitoring-of-individual-spots-on-the-nano-plotter/): Each Nano-Plotter comes with a stroboscopic test of function of each pipet, executed immediately before and after the spotting process for each sample species.
- [Nano-Plotter – Special Applications](https://gesim-bioinstruments-microfluidics.com/nano-plotter-special-applications/): The pipetting instrument Nano-Plotter with its unique piezoelectric GeSiM pipets is primarily used for functionalization of biochips, printing of microarrays and Nanolitre pipetting for multiple parameter assays.
- [Printed Electronics with GeSiM Bioprinters](https://gesim-bioinstruments-microfluidics.com/printed-electronics-with-gesim-bioprinters/): GeSiM bioprinters offer qualitative advantages over the competition. Two important points:
- [Drug Release of Antibiotics through 2-phase 3D-printed Hydrogel Structures](https://gesim-bioinstruments-microfluidics.com/drug-release-of-antibiotics-through-2-phase-3d-printed-hydrogel-structures/): A team from University Hospital Dresden now published a new approach, using the Core/Shell extrusion tool on a GeSiM BioScaffold printer BS3.1. Two different Hydrogels were printed simultaneously in a co-axial arrangement. The 2-phases Core/Shell structure features Alginate for the core-lane at a concentration of 6%, containing suspended antibiotics, different species. Alginate-Methylcellulose (ALG-MC) was used for the shell-lane; its much higher stiffness provides sufficient mechanical strength. ALG-MC was specifically developed by this team.
- [Bioengineering: Ordering Up Organs](https://gesim-bioinstruments-microfluidics.com/bioengineering-ordering-up-organs/): Radio New Zealand (RNZ, “Our Changing World”) interviews the users of a GeSiM BioScaffold printer BS3.1 at University of Otago. It belongs to the core instruments for Dr. Jaydee Cabral, a research fellow at the Chemical Department. She uses the unit successfully since 2017, working on different projects. Beside of biomaterials for bone replacement, her group works with Hydrogels for cell encapsulation.
- [3D Printing of Multi-layer Scaffolds to mimic Patient Specific Implants](https://gesim-bioinstruments-microfluidics.com/3d-printing-of-multi-layer-scaffolds-to-mimic-patient-specific-implants/): Customers at University Hospital of TU Dresden conducted a research study for the future therapy of osteochondral defects. They developed a workflow, based on a magnetic resonance imaging (MRI) dataset derived from a real clinical case. MRI provides more information on cartilage tissue and muscles, surrounding the defect area; whereas X-ray based CT provides a higher resolution but gives contrast for bone structures only.
- [Array-based Chemical Synthesis](https://gesim-bioinstruments-microfluidics.com/array-based-chemical-synthesis/): DNA- and protein microarrays are available for many years, nowadays widely used for modern in-vitro diagnostics. They are based on prefabricated biomolecules, tethered on solid surfaces by special surface chemistry (E.g. Amino-silane slides). When the spotted arrays are exposed to the analyte, just one specific reaction can happen on each spot with high spatial resolution. Single spots can be as small as 100 Microns. The GeSiM Nano-Plotter is a proven tool for preparing these kinds of arrays.
- [We welcome our new partner Bio-Science Kft.](https://gesim-bioinstruments-microfluidics.com/we-welcome-our-new-partner-bio-science-kft/): The company Bio-Science Kft. will support the GeSiM marketing, sales and service activities for the bioprinters in Hungary. Bio-Science – a traditional Hungarian company – sells laboratory equipment to customers in the fields of life science, chemistry and pharmacy. The company is headquartered in Budapest, 24 years old and employs 15 people.
- [Fluidautomation at your Fingertip](https://gesim-bioinstruments-microfluidics.com/fluidautomation-at-your-fingertip/): Hard- and software for automated fluid handling are available in many variations these days. If complexity, flexibility and speed are paramount in your F/E tasks, you should take a look at the new MicCell-FluidProcessor from GeSiM.
- [One Step towards Artifical Liver Models](https://gesim-bioinstruments-microfluidics.com/one-step-towards-artifical-liver-models/): The sophisticated tools of the GeSiM bioprinters enable high-level tissue engineering. Here we present a recent paper published by the Centre for Translational Bone, Joint and Soft Tissue Research at the Faculty of Medicine of TU Dresden.
- [PDMS Spotarrays with the Microarray Printer Nano-Plotter](https://gesim-bioinstruments-microfluidics.com/pdms-spotarrays-with-the-microarray-printer-nano-plotter/): Polydimethylsiloxane (PDMS) is a widely used silicone elastomer with interesting properties such as low cost, biocompatibility and optical transparency. Cost-effective prototypes of flow-through cells are popular in microfluidics. PDMS has a cross-platform meaning for the GeSiM product portfolio: Our microcontact printers do fine and precise surface reliefs featuring 3D stamps made from PDMS. The MicCell is a cost-effective tool kit for microfluidic devices, among others made from PDMS.
- [Melt Electro Writing Scaffolds seeded with Stem Cells](https://gesim-bioinstruments-microfluidics.com/melt-electro-writing-scaffolds-seeded-with-stem-cells/): Melt Electro Writing (MEW) allows to create much smaller pores compared to syringe powered extrusion. Smaller pores are supposed to offer better conditions for cell proliferation.
- [Microfluidics made by GeSiM: The Heart of a State-of-the-Art Water Monitoring System](https://gesim-bioinstruments-microfluidics.com/microfluidics-made-by-gesim-the-heart-of-a-state-of-the-art-water-monitoring-system/): Beside of bioinstruments, 25 years of experience in development of microfluidic flow-through-cells predestine GeSiM as a supplier of microfluidics for sophisticated miniaturized systems for pharmaceutical research, life sciences and biotechnology.
- [GeSiM now sells Bioinks!](https://gesim-bioinstruments-microfluidics.com/gesim-now-sells-bioinks/): We are proud to launch the collaboration with the Korea based company InnoRegen, Inc., better known by their former name Bioink Solutions, Inc. InnoRegen develops and markets bioinks for 3D bioprinting, tissue engineering and 3D cell cultivation since several years. GeSiM is now sales partner, InnoRegen products are available from GeSiM immediately.
- [Melt Deposition Modelling of Bioactive Organic/Inorganic Hybrid Scaffolds](https://gesim-bioinstruments-microfluidics.com/melt-deposition-modelling-of-bioactive-organic-inorganic-hybrid-scaffolds/): Hybrid materials/ blends offer more potential to mimic artificial bones because of better biological/physical properties. E.g. cell adhesion might be much better than for pure PCL. 3D printing of such material, however, could be challenging due to difficult viscoelastic properties. A team at LPC lab (University of Clermont, France) develops hybrid materials consisting of PCL and bioactive glass, respectively. They succeeded in 3D printing of these materials using the mechanical HT-extruder (High-Temperature, High-Pressure Extruder) on a GeSiM BS3.2 bioprinter. Click here for more details.
- [Peptide Chitosan/Dextran Core/Shell vascularized 3D Constructs for Wound Healing](https://gesim-bioinstruments-microfluidics.com/peptide-chitosan-dextran-core-shell-vascularized-3d-constructs-for-wound-healing/): Vascularization is still a challenge when creating artificial tissue by 3D printing. New Zealand researchers successfully put a step forward using the core/shell extruder of the GeSiM bioprinter BS3.1. This tool prints two different materials in a coaxial manner. The team at University of Otago used a bioink with hBMSC stem cells in the shell lane and another biopolymer with endothelial cells in the core lane. In the end microvascularization could be observed. The 3D bioprinted c/s construct made with custom peptide functionalized biomaterials provided a safe delivery vehicle for BMSCs and endothelial cells while providing the appropriate microarchitecture for the early development of vascular, tube-like structures. A first publication is available.
- [An Animal Study for Insulin Delivery by Microneedles](https://gesim-bioinstruments-microfluidics.com/an-animal-study-for-insulin-delivery-by-microneedles/): Microneedle arrays are miniature puncturing devices that disrupt the skin barrier to deliver therapeutic agents trans dermally, in a pain free manner. Common drawbacks associated with typical microneedle coating techniques such as dip-coating, suffer from poor controllability of the outcome in terms of coating morphology, spatial deposition and amount of the drug loaded.

## Pages
- [Liquid Handling Robot](https://gesim-bioinstruments-microfluidics.com/liquid-handling-robot/): The compact liquid handling robot BioSyntheSizer from GeSiM manifests a new instrumentation concept for robots for complex laboratory automation on low-volume scale. It’s a very compact lab automation platform whose goal is utmost flexibility. This liquid handling robot offers all usual tools for automated pipetting: Pick-up and displacement of pipet tips, automatic lid opening/closing, manipulation of vials, tubes and more. On top, it can be extended with the proven GeSiM Picolitre pipetting technology based on piezoelectric micropipettes.
- [Newsletter Subscription Management](https://gesim-bioinstruments-microfluidics.com/newsletter-subscription-management/): Subscription management form is only available to mailing lists subscribers.
- [Newsletter Unsubscribe Confirmation](https://gesim-bioinstruments-microfluidics.com/newsletter-unsubscribe-confirmation/):   Newsletter Unsubscribe Confirmation
- [Join our mailing list!](https://gesim-bioinstruments-microfluidics.com/join-our-mailing-list/): We are sending occasional newsletters with up-to-date information on the GeSiM Nano-Plotter. This will happen not very frequently, about once per months. Please enter your email address to join!
- [Newsletter Unsubscribe](https://gesim-bioinstruments-microfluidics.com/newsletter-unsubscribe/):       Newsletter Unsubscribe We are sorry to see you go. Herewith we confirm your newsletter cancellation.      
- [Newsletter confirmation](https://gesim-bioinstruments-microfluidics.com/newsletter-confirmation/): Thanks for your interest in our newsletter
- [Thanks for contacting us!](https://gesim-bioinstruments-microfluidics.com/weiterleitung/):         Thanks for contacting us! We appreciate your time and we will get back to you as soon as possible.        
- [Datenschutz / Data Protection](https://gesim-bioinstruments-microfluidics.com/datenschutz-data-protection/): Wir freuen uns sehr über Ihr Interesse an unserem Unternehmen. Datenschutz hat einen besonders hohen Stellenwert für die Geschäftsleitung der GeSiM – Gesellschaft fuer Silizium-Mikrosysteme mbH. Eine Nutzung der Internetseiten der GeSiM – Gesellschaft fuer Silizium-Mikrosysteme mbH ist grundsätzlich ohne jede Angabe personenbezogener Daten möglich. Sofern eine betroffene Person besondere Services unseres Unternehmens über unsere Internetseite in Anspruch nehmen möchte, könnte jedoch eine Verarbeitung personenbezogener Daten erforderlich werden. Ist die Verarbeitung personenbezogener Daten erforderlich und besteht für eine solche Verarbeitung keine gesetzliche Grundlage, holen wir generell eine Einwilligung der betroffenen Person ein.
- [Site Notice](https://gesim-bioinstruments-microfluidics.com/site-notice/): Copyright (c) 2003 – 2026 GeSiM. All Rights reserved. All trademarks used or referred to in this site are the property of their respective owners.
- [AGB](https://gesim-bioinstruments-microfluidics.com/agb/): 1. Für alle Geschäfte mit Unternehmern (hier „Kunden“) gelten UNSERE VERKAUFS- UND LIEFERBEDINGUNGEN. Diese haben auch dann Gültigkeit, wenn nicht jeweils besonders auf sie Bezug genommen wird.
- [Microfluidics](https://gesim-bioinstruments-microfluidics.com/microfluidics/): Please don't miss the MicCell, a separate GeSiM product line for polymer microfluidics with microscope interface.
- [Bioprinter](https://gesim-bioinstruments-microfluidics.com/bioprinter/): The BS3.3 Prime is the new affordable bioprinter from GeSiM, including a set of tools for easy printing of most popular bioinks. It comes with the full software package known from the larger GeSiM bioprinters.
- [Microcontact Printers](https://gesim-bioinstruments-microfluidics.com/microcontact-printer/): Microcontact Printer µCP6.3Micromachining to perfection: µCP6.3 combines two lithography methods for transparent targets. Nanoimprint lithography on the upper level and optical lithography on the lower level allow complex microfluidic patterns in a single step.
- [Microscopy Cell – Customizable Tool Kit for Micro Biology](https://gesim-bioinstruments-microfluidics.com/microscopy-cell/): For R/D purposes the MicCell Microscopy Cell combines an affordable casting process using PDMS and a convenient mechanical setup for quick replacement of the used PDMS channel plate. The mechanical frame of the MicCell fits on standard microscope stages.
- [International Distributors](https://gesim-bioinstruments-microfluidics.com/international-distributors/): Please feel free to contact us at any time. With respect to the time gaps across the world, our international distributors will accept your request as well.
- [Career](https://gesim-bioinstruments-microfluidics.com/career/): There are currently no open positions.
- [Publications and Resources](https://gesim-bioinstruments-microfluidics.com/publications/): GeSiM bioinstruments and microfluidics are mostly placed into a scientific environment. We are proud to present customer projects conducted with our products. All publications are listed chronologically. Searching of your specific topic of interest is possible by using the seach field on top of each table.
- [Expositions and Events](https://gesim-bioinstruments-microfluidics.com/expositions-events/): Here you will find events where you can meet us in person and experience GeSiM products in action.
- [Bioinstruments and Microfluidics – About GeSiM](https://gesim-bioinstruments-microfluidics.com/about-us/): GeSiM was founded 1995 as a spin-off from the Rossendorf Research Center. The company is a non-public and privately held entity.
- [Contact](https://gesim-bioinstruments-microfluidics.com/contact/): Please click the button below for a list of our international distributors. International Distributors   Contact to GeSiM Please enable JavaScript in your browser to complete this form.Organization *Name *FirstLastPhoneJob TitleEmail Address *Subject *GDPR Agreement *I consent to having this website store my submitted information so they can respond to my inquiry.Spam control * = Submit
- [Nanolitre Dispensers](https://gesim-bioinstruments-microfluidics.com/nanolitre-dosage/): GeSiM Nanolitre dispensers (also called “pipettes” or “jets”) follow the drop-on-demand principle, i.e., a drop is released exactly when the piezo ceramic actuator is triggered. This results in the bending of a silicon diaphragm behind the actuator and this in turn leads to a compression of the liquid inside the “pump chamber” and hence to the ejection of a droplet from the nozzle. After this, the ceramic returns to its initial state and the dispenser is refilled with liquid from the inlet. No valve is involved in this process.
- [Microarray Printer](https://gesim-bioinstruments-microfluidics.com/microarray-printer/): NP2.1: One Platform, Two SizesThe microarray printer Nano-Plotter 2.1 TM family is ideal to generate high-quality spots by non-contact microdispensing of sub-naoliter volumes.
- [GeSiM Bioinstruments and Microfluidics](https://gesim-bioinstruments-microfluidics.com/): Below you find key points of realized applications. The tabs toggle through the different GeSiM product lines.

## Categories
- [News](https://gesim-bioinstruments-microfluidics.com/news/)